Sequential intracoelomic and intrabursal immunization of chickens with inactivated Mycoplasma gallisepticum bacterin and iota carrageenan adjuvant.

摘要: Chickens immunized by sequential intracoelomic (analogous to intraperitoneal route in mammals) and intrabursal (i.c./i.b.) routes with inactivated Mycoplasma gallisepticum (MG) bacterin mixed 0.2% iota carrageenan (iCGN) as an adjuvant were resistant airsacculitis induced a subsequent aerosol challenge virulent R strain MG. In contrast, immunization the i.c./i.b. without or iCGN did not confer significant protection. adjuvanted had increased levels of circulating local anti-MG IgG but IgM IgA. Tracheal populations MG reduced when compared unimmunized controls.