Transcriptional coactivator p300 regulates glucose-induced gene expression in endothelial cells

作者: Shali Chen , Biao Feng , Biju George , Rana Chakrabarti , Megan Chen

DOI: 10.1152/AJPENDO.00432.2009

关键词: Diabetes mellitusMessenger RNATranscription factorTranscriptional CoactivatorTissue damageRNAEndothelial stem cellBiologyGene expressionMolecular biology

摘要: Sustained hyperglycemia in diabetes causes alteration of a large number of transcription factors and mRNA transcripts, leading to tissue damage. We investigated whether p300, a …

参考文章(55)
Tetsuhiko Yanazume, Biological role of p300 in cardiac myocytes. Molecular and Cellular Biochemistry. ,vol. 248, pp. 115- 119 ,(2003) , 10.1023/A:1024132217870
Enrico Cagliero, Mara Lorenzi, Sayon Roy, Fibronectin overexpression in retinal microvessels of patients with diabetes. Investigative Ophthalmology & Visual Science. ,vol. 37, pp. 258- 266 ,(1996)
Joan Boyes, Peter Byfield, Yoshihiro Nakatani, Vasily Ogryzko, Regulation of activity of the transcription factor GATA-1 by acetylation Nature. ,vol. 396, pp. 594- 598 ,(1998) , 10.1038/25166
Wu-Guo Deng, Kenneth K. Wu, Regulation of Inducible Nitric Oxide Synthase Expression by p300 and p50 Acetylation Journal of Immunology. ,vol. 171, pp. 6581- 6588 ,(2003) , 10.4049/JIMMUNOL.171.12.6581
Galina V. Shurin, Robert Ferris, Irina L. Tourkova, Lori Perez, Anna Lokshin, Levent Balkir, Bobby Collins, Gurkamal S. Chatta, Michael R. Shurin, Loss of New Chemokine CXCL14 in Tumor Tissue Is Associated with Low Infiltration by Dendritic Cells (DC), while Restoration of Human CXCL14 Expression in Tumor Cells Causes Attraction of DC Both In Vitro and In Vivo Journal of Immunology. ,vol. 174, pp. 5490- 5498 ,(2005) , 10.4049/JIMMUNOL.174.9.5490
Sarah Smolik, Richard H. Goodman, CBP/p300 in cell growth, transformation, and development Genes & Development. ,vol. 14, pp. 1553- 1577 ,(2000) , 10.1101/GAD.14.13.1553
George L. King, Michael Brownlee, The cellular and molecular mechanisms of diabetic complications. Endocrinology and Metabolism Clinics of North America. ,vol. 25, pp. 255- 270 ,(1996) , 10.1016/S0889-8529(05)70324-8
Wolfgang Fischle, Yanming Wang, C David Allis, Histone and chromatin cross-talk Current Opinion in Cell Biology. ,vol. 15, pp. 172- 183 ,(2003) , 10.1016/S0955-0674(03)00013-9
Jane Chiu, Zia A. Khan, Hana Farhangkhoee, Subrata Chakrabarti, Curcumin prevents diabetes-associated abnormalities in the kidneys by inhibiting p300 and nuclear factor-κB Nutrition. ,vol. 25, pp. 964- 972 ,(2009) , 10.1016/J.NUT.2008.12.007