Peritoneal endometriosis and “endometriotic” nodules of the rectovaginal septum are two different entities**Supported by Fonds de la Recherche Scientifique, grant no. 3.4587.90, Brussels, Belgium and a grant from Ipsen Biotech, Paris, France.

作者: Jacques Donnez , Michelle Nisolle , Pierre Smoes , Nadine Gillet , Sandrine Beguin

DOI: 10.1016/S0015-0282(16)58501-X

关键词: BiopsyMetaplasiaEndometriosisVimentinNodule (medicine)AdenomyomaAdenomyosisPathologyCytokeratinMedicine

摘要: OBJECTIVE: To compare histologically and stereologically the endometriotic nodule of rectovaginal septum to peritoneal endometriosis. DESIGN: Morphometric investigation, cytokeratin vimentin content, steroid receptor evaluation were performed on tissue from peritoneum (n = 52) nodules 68). SETTING: An academic teaching hospital. PATIENTS: Biopsies taken 120 patients undergoing a laparoscopy for infertility and/ or pelvic pain (52 typical black implants 68 septum). None treated. RESULTS: Mitotic activity was found be significantly different in The suggested that stroma is not mandatory invasion glandular epithelium nodule, which is, like adenomyoma, circumscribed nodular aggregate smooth muscle elements. Cytokeratin content as well estrogen (ER) P (PR) lower both types lesion when compared with eutopic endometrium. But immunoreactivity epithelium, ER PR lesions. CONCLUSION: It disease endometriosis must called adenomyosis adenomyoma. Its histopathogenesis probably related implantation regurgitated endometrial cells but metaplasia Mullerian rests.

参考文章(25)
F McGlynn, H Reich, J Salvat, Laparoscopic treatment of cul-de-sac obliteration secondary to retrocervical deep fibrotic endometriosis. Journal of Reproductive Medicine. ,vol. 36, pp. 516- 522 ,(1991)
Yoshiaki Hirama, Kazunori Ochiai, Estrogen and progesterone receptors of the out-of-phase endometrium in female infertile patients. Fertility and Sterility. ,vol. 63, pp. 984- 988 ,(1995) , 10.1016/S0015-0282(16)57534-7
Dan C. Martin, Gary D. Hubert, Roger Vander Zwaag, Faten A. El-Zeky, Laparoscopic appearances of peritoneal endometriosis Fertility and Sterility. ,vol. 51, pp. 63- 67 ,(1989) , 10.1016/S0015-0282(16)60429-6
P.R. Koninckx, D.C. Martin, Deep endometriosis: a consequence of infiltration or retraction or possibly adenomyosis externa? Fertility and Sterility. ,vol. 58, pp. 924- 928 ,(1993) , 10.1016/0020-7292(93)90483-D
J.W. Roddick, G. Conkey, E.J. Jacobs, The hormonal response of endometrium in endometriotic implants and its relationship to symptomatology American Journal of Obstetrics and Gynecology. ,vol. 79, pp. 1173- 1177 ,(1960) , 10.1016/0002-9378(60)90531-7
Charles Zaloudek, Henry J. Norris, Mesenchymal Tumors of the Uterus Springer, New York, NY. pp. 373- 408 ,(1987) , 10.1007/978-1-4757-1942-0_13
Jacques Donnez, Françoise Casanas-Roux, Jacques Caprasse, Jacques Ferin, Karl Thomas, Cyclic changes in ciliation, cell height, and mitotic activity in human tubal epithelium during reproductive life Fertility and Sterility. ,vol. 43, pp. 554- 559 ,(1985) , 10.1016/S0015-0282(16)48496-7
Michelle Nisolle, Françoise Casanas-Roux, Christine Wyns, Yvan de Menten, Pierre-Emmanuel Mathieu, Jacques Donnez, Immunohistochemical analysis of estrogen and progesterone receptors in endometrium and peritoneal endometriosis: a new quantitative method. Fertility and Sterility. ,vol. 62, pp. 751- 759 ,(1994) , 10.1016/S0015-0282(16)57000-9
Michelle Nisolle, Bénédicte Paindaveine, Anne Bourdon, Martine Berlière, Françoise Casanas-Roux, Jacques Donnez, Histologic study of peritoneal endometriosis in infertile women Fertility and Sterility. ,vol. 53, pp. 984- 988 ,(1990) , 10.1016/S0015-0282(16)53571-7