Oxazolidinone containing dimer compounds, compositions and methods to make and use

摘要: Dosage forms or pharmaceutical compositions comprise a compound having the structure of Formula (IV) wherein n is non-negative integer; each Z an oxazolidinone-containing moiety antibiotic activity in vivo upon cleaving, M independently OR1 NR1R2; R1 and R2 are selected from group consisting H, optionally-substituted hydrocarbyl residue pharmaceutically acceptable cation; dosage form composition present amount effective for treating preventing antibacterial infection mammalian subject. Methods preparing using these also disclosed.