The electrochemical investigation of carboxamide-PEG2-biotin-CoPc using composite MWCNTs on modified GCE: the sensitive detections for glucose and hydrogen peroxide

摘要: The electroanalytical study of a synthesized novel tetra-cobalt(II) carboxamide-PEG2-biotin phthalocyanine (CoTPEG2BAPc) composite with MWCNTs to create biosensor high response glucose in the presence H2O2. can be easily detected by casting onto GCE, and it displays intrinsic electrocatalytic ability for enzymatic oxidation reduction H2O2, showing higher catalytic activity than that bulk CoTPEG2BAPc electrode. Under optimal conditions, shows wide linear (CV: 2–16; DPV: 2–22; CA: 5–50 μmol) H2O2 5–25; μmol), good sensitivity towards 0.947; 1.978; 0.101 μA μM−1 cm−2) 1.250; 1.888; 0.162 cm−2), stable long-term life LOD 0.33; 2; 12.5 μmol L−1) 1.5; 5; 10 L−1). amperometry selectivity studies involving different biomolecules, including AA, DA, UA, L-cysteine, glycine, show they do not affect determination. Our present work exhibits very attractive practical performance applications.