The clinical effect of a single direct topical application of a dentifrice containing 8.0% arginine, calcium carbonate, and 1450 ppm fluoride on dentin hypersensitivity: the use of a cotton swab applicator versus the use of a fingertip.

摘要: Objective The primary objective of this examiner-blind, randomized clinical study was to compare the effect a toothpaste containing 8.0% arginine, calcium carbonate, and 1450 ppm fluoride, as sodium monofluorophosphate (MFP), in providing instant relief dentin hypersensitivity when delivered single direct topical application using cotton swab applicator versus fingertip. A secondary evaluate on dentifrice after seven days twice-daily at-home brushing, subsequent performed at beginning study. Methods Qualifying subjects possessed two baseline-designated hypersensitive teeth with tactile score 10 50 grams force (Yeaple Probe), an air blast 2 or 3 (Schiff Cold Air Sensitivity Scale). In first phase study, topically self-applied test product fingertip, previously validated method, for one (fingertip teeth), second tooth (swab teeth). brushed twice daily days. Dentin assessments, well examinations oral hard soft tissues, were conducted immediately application, seven-day brushing period. Results Eighty-four complied protocol completed Immediately fingertip exhibited statistically significant (p 0.05) differences indicated between respect mean scores (3.4% 4.4%, respectively), (0.41% -1.90%, respectively). Conclusion results examiner-blind support conclusions that 1) both methods provide reductions arginine-calcium carbonate dentifrice, 2) is followed by sensitivity obtained instantly maintained, 3) neither method provided level control differed significantly from other.