Role of Growth Factors and Cytokines in the Therapy of Immune Deficiencies

作者: Sudhir Gupta

DOI: 10.1007/978-1-4612-2616-1_10

关键词: Colony-stimulating factorImmunodeficiencyCommon variable immunodeficiencyInterferon gammaHaematopoiesisInterleukin 2ImmunologyImmune systemMedicineMonocyte

摘要: During the 1980s, rapid progress was made in better understanding of pathogenesis immunodeficiencies at both cellular and molecular levels. Furthermore, development recombinant techniques has led to cloning, expression, formulation a number hematopoietic growth factors cytokines that have become more affordable whose potential therapeutic uses been explored. The purpose this chapter is briefly review scope certain already used or future therapy immunodeficiency disorders. An attempt summarize biological characteristics these factors, defects pertinent diseases, results Among granulocyte-colony stimulating factor (G-CSF) granulocyte monocyte colony (GM-CSF) will be discussed. cytokines, interleukin 2 (IL-2) interferon gamma (IFN-y) reviewed.

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