Progression of pancreatic cystic lesions without any risk features is associated with initial cyst size and obesity.

作者: Hye Won Park , Jong Soo Lee , Seo Young Park , Tae Hyup Kim , Ji Young Lee

DOI: 10.1111/JGH.14940

关键词: Retrospective cohort studyMalignancyObesityClinical significancePopulationGastroenterologyCystAsymptomaticCystic lesionMedicineInternal medicine

摘要: Background and aim The clinical significance of incidental pancreatic cystic lesions (PCLs) remains unclear in those that are not accompanied by worrisome features or high-risk stigmata. We aimed to investigate the natural course PCLs without any risk examine factors associated with their progression. Methods conducted a retrospective cohort study 427 patients PCLs, which were incidentally detected computed tomography between January 2003 December 2012. Progression progression investigated. length time significant growth was also evaluated. Results Ninety-four (22.0%) had asymptomatic showed after median surveillance period 5.3 years; approximately 27.7% size changes first 5 years, while remaining 72.3% years. cumulative rate initial cyst high body mass index. In group, additional treatments required for 12 patients, one whom developed malignancy. Four stable group underwent treatment no malignant change. Conclusions One-fifth significantly increased long-term follow-up period, obesity. mostly although malignancy low, it still concern.

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