Chapter 2 – MALDI-TOF Mass Spectrometry for Microorganism Identification

作者: Lori Bourassa , Susan M. Butler-Wu

DOI: 10.1016/BS.MIM.2015.07.003

关键词: MicroorganismBiologyClinical microbiologyIdentification (biology)MALDI-TOF Mass SpectrometryMass spectrometryMatrix-assisted laser desorption/ionizationChromatography

摘要: Matrix-assisted laser desorption ionisation time-of-flight mass spectrometry (MALDI-TOF MS) is a rapid, accurate and high-throughput method for microorganism identification. MALDI-TOF MS identification of microorganisms has revolutionised the clinical microbiology laboratory offering species-level identifications in minutes with accuracy that matches often exceeds conventional systems. This chapter summarises performance characteristics commercially available systems bacteria, yeasts filamentous fungi. The directly from select specimens also discussed.

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