Impact of gas(less) laparoscopy and laparotomy on peritoneal tumor growth and abdominal wall metastases

摘要: Objective A tumor model in the rat was used to study peritoneal growth and abdominal wall metastases after carbon dioxide (CO 2 ) pneumoperitoneum, gasless laparoscopy, laparotomy. Background Data The role of laparoscopic resection cancer is under debate. Insufflation cavity with CO believed be a causative factor development malignant tumors. Methods In solid model, lump 350-mg CC-531 cells placed intraperitoneally rats having pneumoperitoneum (n = 8), laparoscopy or conventional laparotomy 8). After 20 minutes, removed through port cell seeding 5 x 10 were injected before 12), 12). All operative procedures lasted minutes. 6 weeks, 4 weeks scored semiquantitatively. results analyzed using analysis variance. Results group greater than (p < 0.01). Peritoneal size at site extraction other sites 0.001). comparison 0.02). Conclusions following conclusions can made: 1) that direct contact between enhances local growth, 2) associated less intraperitoneal laparotomy, 3) insufflation promotes peritoneum laparoscopy.