Elevated plasma interleukin-6 levels in patients with acute myocardial infarction
作者： Yuji Miyao , Hirofumi Yasue , Hisao Ogawa , Ikuo Misumi , Takenobu Masuda
DOI: 10.1016/0002-8703(93)90526-F
关键词: Interleukin 6 、 Liter 、 Medicine 、 Surgery 、 Myocardial infarction 、 Cardiac catheterization 、 Pulmonary wedge pressure 、 In patient 、 Internal medicine 、 Creatine kinase 、 Ejection fraction 、 Cardiology
摘要: Interleukin-6 (IL-6) plays a key role in the synthesis of human acute-phase protein and several responses occur patients with acute myocardial infarction (AMI). We examined plasma levels IL-6 23 consecutive AMI over course 4 weeks 30 control subjects. In AMI, (in picograms per milliliter) were increased at all sampling points from admission to discharge (ranging 28.5 ± 6.6 46.5 7.8) compared subjects (11.4 2.9; p < 0.01). Cardiac catheterization did not influence levels. The level reached its peak approximately 3 days (46.5 1 week after AMI. There was significant positive linear correlation between minus on C-reactive correlate creatine kinase, pulmonary capillary wedge pressure, or left ventricular ejection fraction weeks. conclude that is time
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