Aptamer-based optical probes with separated molecular recognition and signal transduction modules.

作者： Na Li , Chih-Ming Ho

关键词: Oligonucleotide 、 RNA 、 Small molecule 、 Molecular recognition 、 Chemistry 、 Aptamer 、 Highly sensitive 、 DNA 、 Signal transduction 、 Nanotechnology 、 Biophysics

摘要: … design strategy for aptamer-based optical bio-sensors, in which an unmodified aptamer … The signaling competitor oligo is completely or partially complementary to the aptamer. In …