Autopsy pathology in the acquired immune deficiency syndrome.

摘要: The acquired immune deficiency syndrome (AIDS) is a devastating new illness which appears to be sexually and parenterally transmissible. AIDS was first described in the male homosexual community; however, disease has more recently been among intravenous drug abusers, Haitians, hemophiliacs, others. etiologic agent unknown. may represent an infection by previously undescribed organism, mutant of known microorganism, or multifactorial combination environmental, immunologic, genetic factors. As consequence disease's seemingly irreversible ablation cell-mediated system, victims succumb variety infections and/or unusual neoplasms. In its fully developed form, mortality approaches 100%. At autopsy gross microscopic pathology can divided into three general categories: 1) morphologic manifestations profound lymphoid depletion; 2) infections, usually with mixed opportunistic pathogens; 3) neoplasms, most frequently Kaposi's sarcoma high-grade lymphomas.