Transcriptome sequencing revealsmaelstromas a novel target gene of the terminal system in the red flour beetleTribolium castaneum

摘要: Terminal regions of the Drosophila embryo are patterned by localized activation Torso-RTK pathway, which promotes downregulation Capicua. In short-germ beetle Tribolium, function terminal system appears to be rather different, as pathway axis elongation and, in addition, is required for patterning extra-embryonic serosa at anterior. Here, we show that Torso signalling also induces gene expression relieving Capicua-mediated repression Tribolium Given majority target genes remain identified, established a differential gene-expression screen. A subset 50 putative was screened functions early embryonic patterning. Of those, 13 domains and phenotypes were related Among others, found PIWI-interacting RNA factor Maelstrom crucial polarization. Tc-mael proper serosal size regulation head morphogenesis. Moreover, growth-zone formation elongation. Our results suggest posterior may realized through Maelstrom-dependent Wnt domains.