Contractile efficiency of dystrophic mdx mouse muscle: in vivo and ex vivo assessment of adaptation to exercise of functional end points.

作者: Roberta Francesca Capogrosso , Paola Mantuano , Anna Cozzoli , Francesca Sanarica , Ada Maria Massari

DOI: 10.1152/JAPPLPHYSIOL.00776.2015

关键词: Standard protocolEx vivomdx mouseIn vivoMedicineMaladaptationTreadmill exerciseDuchenne muscular dystrophyPhysical medicine and rehabilitationNeuroscience

摘要: We focused on the adaptation/maladaptation of dystrophic mdx mouse muscles to a standard protocol exercise provide guidance in development more effective drug and physical therapies in...

参考文章(58)
Annamaria De Luca, Pre-clinical drug tests in the mdx mouse as a model of dystrophinopathies: an overview. Acta myologica : myopathies and cardiomyopathies : official journal of the Mediterranean Society of Myology / edited by the Gaetano Conte Academy for the study of striated muscle diseases. ,vol. 31, pp. 40- 47 ,(2012)
Thomas, J. Burkholder, Mechanotransduction in skeletal muscle Frontiers in Bioscience. ,vol. 12, pp. 174- 191 ,(2007) , 10.2741/2057
G. D. Wadley, J. Choate, G. K. McConell, NOS isoform‐specific regulation of basal but not exercise‐induced mitochondrial biogenesis in mouse skeletal muscle The Journal of Physiology. ,vol. 585, pp. 253- 262 ,(2007) , 10.1113/JPHYSIOL.2007.141309
O. R. Joassard, G. Belanger, J. Karmouch, J. A. Lunde, A. H. Shukla, A. Chopard, C. Legay, B. J. Jasmin, HuR Mediates Changes in the Stability of AChR β-Subunit mRNAs after Skeletal Muscle Denervation. The Journal of Neuroscience. ,vol. 35, pp. 10949- 10962 ,(2015) , 10.1523/JNEUROSCI.1043-15.2015
Claudia Colussi, Chiara Mozzetta, Aymone Gurtner, Barbara Illi, Jessica Rosati, Stefania Straino, Gianluca Ragone, Mario Pescatori, Germana Zaccagnini, Annalisa Antonini, Giulia Minetti, Fabio Martelli, Giulia Piaggio, Paola Gallinari, Christian Steinkuhler, Emilio Clementi, Carmela Dell'Aversana, Lucia Altucci, Antonello Mai, Maurizio C Capogrossi, Pier Lorenzo Puri, Carlo Gaetano, HDAC2 blockade by nitric oxide and histone deacetylase inhibitors reveals a common target in Duchenne muscular dystrophy treatment Proceedings of the National Academy of Sciences of the United States of America. ,vol. 105, pp. 19183- 19187 ,(2008) , 10.1073/PNAS.0805514105
Joshua T. Selsby, Pedro Acosta, Meg M. Sleeper, Elisabeth R. Barton, H. Lee Sweeney, Long-term wheel running compromises diaphragm function but improves cardiac and plantarflexor function in the mdx mouse. Journal of Applied Physiology. ,vol. 115, pp. 660- 666 ,(2013) , 10.1152/JAPPLPHYSIOL.00252.2013
Thomas G. Burch, Russell L. Prewitt, Peter K. Law, In vivo morphometric analysis of muscle microcirculation in dystrophic mice. Muscle & Nerve. ,vol. 4, pp. 420- 424 ,(1981) , 10.1002/MUS.880040511
Glen B. Banks, Jeffrey S. Chamberlain, Stanley C. Froehner, Truncated dystrophins can influence neuromuscular synapse structure Molecular and Cellular Neuroscience. ,vol. 40, pp. 433- 441 ,(2009) , 10.1016/J.MCN.2008.12.011
Yi Lai, Gail D. Thomas, Yongping Yue, Hsiao T. Yang, Dejia Li, Chun Long, Luke Judge, Brian Bostick, Jeffrey S. Chamberlain, Ronald L. Terjung, Dongsheng Duan, Dystrophins carrying spectrin-like repeats 16 and 17 anchor nNOS to the sarcolemma and enhance exercise performance in a mouse model of muscular dystrophy Journal of Clinical Investigation. ,vol. 119, pp. 624- 635 ,(2009) , 10.1172/JCI36612
Anna Cozzoli, Roberta Francesca Capogrosso, Valeriana Teresa Sblendorio, Maria Maddalena Dinardo, Catherine Jagerschmidt, Florence Namour, Giulia Maria Camerino, Annamaria De Luca, GLPG0492, a novel selective androgen receptor modulator, improves muscle performance in the exercised-mdx mouse model of muscular dystrophy Pharmacological Research. ,vol. 72, pp. 9- 24 ,(2013) , 10.1016/J.PHRS.2013.03.003