DALDA (H-Tyr-D-Arg-Phe-Lys-NH2), a potent μ-opioid peptide agonist, affects various patterns of locomotor activities

作者: M Meyer

DOI: 10.1016/0091-3057(94)00308-6

关键词: AgonistReceptorOpioid peptideLocomotor activitiesChemistryStereotypy (non-human)Internal medicineEndocrinology

摘要: Abstract The central effects of μ-opioid receptor agonist DALDA (ICV 0.00, 0.1, or 1.0 μg) were investigated in rats for 120 min on activity monitors. durations seconds horizontal movement time, rearing and stereotypy time measured during 12 consecutive 10-min blocks. (ICV, 0.1 resulted biphasic effects, inhibition followed by activation movement, rearing, times.

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