[The use of nationwide tuberculosis surveillance system data to determine geographical differences in drug resistance--consideration of the representativeness of the drug resistance rate in Japan].

摘要: Annual reports of tuberculosis (TB) statistics have been compiled using a database built through the nationwide computerized TB surveillance system in Japan. Using annual report for 2007-2009, this study compared drug resistance rates among eight geographical districts. The proportion bacteriological test results obtained at public health centers, which enter data into their computers that can then be accessed by central computer, improved greatly from 2007 to 2009. initial culture pulmonary increased 63.8% 74.8% and susceptibility culture-positive cases 41.8% 63.5%. As result, 15,425 (26.5%) 58,198 newly notified during three-year period were obtained. multi-drug resistant (MDR) new treatment patients was 0.6% whole country. Although there no particular districts having significantly high rate MDR-TB, Kinki district showed highest 0.8%. In case retreatment patients, MDR-TB 5.1% country statistical difference any INH 4.5% country, with Kanto showing 5.3% 5.2%, respectively. 13.3% where high. one or more drugs 12.7% higher 15.4%. 22.2% It is important monitor comprehensive control program. tests revealed tendency toward included large cities. many problems remain solved order optimize use represent Japan, practice expected yield great benefits.