Role of the stretch reflex in oxotremorine tremor.

作者: Emilio E. Decima

DOI: 10.1016/0024-3205(96)00196-8

关键词: ShiveringAtropineAnesthesiaDorsumAgonistChemistryHindlimbStretch reflexRhizotomyOxotremorineAnatomy

摘要: Abstract Although the basic mechanism for parkinsonian tremor is known to be central, case oscillator(s) of physiological and shivering still a matter dispute. In this case, an important role has been proposed muscle afferents. Oxotremorine in common with its frequency range (10–28 Hz) co-contraction flexors extensors. On other hand, contradistinction, it can blocked by atropine, as tremor. Thus was interest analyze afferents production maintenance oxotremorine acutely decorticated cat. This studied two experimental approaches. one, either front or hind limb cat completely deafferented dorsal rhizotomy activity recorded electromyographycally pair antagonistic muscles. other, nerve electrical force produced tremoring (gastrocnemius) were simultaneously. Tremor induced injection (200–750 μg/kg i.p.) given at different postoperative periods. The drug regular chronically animals (3 weeks 5 months) but not hrs after rhizotomy). observed former group very had same both normal deafferentd sides. Section all pool (agonist main Synergist) did have any effect on regularity oscillation (tremor) that pool. and/or cutaneous afferents, although perhaps some importance, remains unclear. A pure spinal account oscillations proposed.

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