作者: Arie Katz , Chandrasekhar Udata , Elyssa Ott , Lisa Hickey , Michael E. Burczynski
关键词: Liver X receptor 、 Biology 、 Pharmacokinetics 、 Population 、 ABCA1 、 Agonist 、 Reverse cholesterol transport 、 Cholesterol 、 Pharmacodynamics 、 Pharmacology
摘要: … In this study, we administered either LXR-623, a novel LXR α and β agonist, or placebo to … LXR-623 was absorbed relatively rapidly following oral administration. LXR-623 plasma …