Amplified DNA Analysis and Single-Base Mismatch Detection Using DNA-Bioelectronic Systems

作者: Itamar Willner , Amir Lichtenstein , Fernando Patolsky

DOI: 10.14891/ANALSCISP.17ICAS.0.I351.0

关键词: DNAChemistryDna detectionLiposomeBiophysicsNucleic acidDna recognitionMutationMutant

摘要: Methods for the amplified detection of DNA are discussed. These include: (i) The biocatalyzed precipitation an insoluble product or catalyzed deposition gold as (bio)chemical transformations that follow recognition events. (ii) use particulate amplifying labels such liposomes, Au-nanoparticles CdS-nanoparticles. A further aspect is addressed includes single-base mismatch in a nucleic acid mutant. method coupling labeled-base complementary to mutation site and Electrochemical, microgravimetric photoelectrochemical techniques employed transduce processes.

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