TEMAZEPAM AND TRIMEPRAZINE COMPARED WITH PLACEBO AS PREMEDICATION IN CHILDREN An Investigation Extended into the First 2 Weeks at Home

作者: N.L. PADFIELD , M. MCD. TWOHIG , A.C.L. FRASER

DOI: 10.1093/BJA/58.5.487

关键词: Randomized controlled trialAnesthesiaPremedicationHypnoticAlimemazinePlaceboTrimeprazineMedicineSedationTemazepam

摘要: Temazepam, trimeprazine and placebo were compared as premedication in 85 children undergoing routine otolaryngological operations. Premedication with caused significantly more sedation than temazepam or patients on arrival the anaesthetic room (P less 0.02). Recovery time was longer after 0.012). Significantly 0.05) failed to recall a picture shown immediately before induction placebo. Fewer vomited operation 0.01). The majority of exhibited some behavioural problem during first 2 weeks at home, although this rarely lasted for few days. More apathetic/withdrawn behaviour receiving 0.05), significance should be interpreted caution.

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