Solid‐State Nuclear Magnetic Resonance

摘要: The first experimental verification of nuclear magnetic resonance (NMR) in the solid state was carried out by Edward M. Purcell, Henry C. Torrey, and Robert V. Pound 1945. Since then, new developments have transformed this form spectroscopy from an interesting physical curiosity at its inception to one most widely used analytical tools for physical, chemical, biological, materials research applications. capabilities NMR include following: identification molecules all phases matter their atomic connectivities; probing temperature-dependent conformation cyclohexane complex 50 kDa proteins; molecular dynamics investigations picosecond timescale rotation small second atoms diffusing throughout three-dimensional nanoscopic channels zeolites; elucidation chemical reaction mechanisms; determination organization, reorientation, diffusion solids; phase changes morphology measurement bond lengths interatomic distances between nonbonded atoms; assessment pore size nanoporous solids as well adsorbates diffusivities; estimation physicochemical parameters systems such equilibrium kinetic rate constants, enthalpies entropies a reaction, activation energies; capability follow metabolic pathway taking place inside living cells; quantification alignment partially ordered systems; nanoscale domain sizes heterogeneous materials; noninvasive imaging forms under various temperature, pressure, mechanical conditions. The scope article is very selective, covering some techniques more unusual areas application solid-state NMR. These topics are covered different levels detail, just mentioned reference published work. This not intended present comprehensive review state-of-the-art techniques; these, reader should consult references included text. Instead, provides historical background fundamental concepts that preceded NMR, general overview basic principles with emphasis on visualization anisotropic spin interactions, methods investigating practical information provide modicum guidance methods. There several redundancies terminology so sections can be read independently. The important component consulted complete often original accounts theory solids. A modest attempt has been made references, but importantly, many examples insights obtained whole or part investigation problem. For figures tables, if no acknowledgment provided, spectrum photograph figure table previously unpublished. The directed audience scientists interest In addition, spectroscopists may find details studies metals materials. Keywords: solid; tensor; induced field; resonance surface; magic angle spinning; anisotropy; spin relaxation; shielding; Knight shift; quadrupole moment; Rabi field; molecular beam; T-field