Hierarchical tailoring of strut architecture to control permeability of additive manufactured titanium implants.

摘要: Porous titanium implants are a common choice for bone augmentation. Implants spinal fusion and repair of non-union fractures must encourage blood flow after implantation so that there is sufficient cell migration, nutrient growth factor transport to stimulate ingrowth. Additive manufacturing techniques allow large number pore network designs. This study investigates how the design factors offered by selective laser melting technique can be used alter implant architecture on multiple length scales control even tailor flow. Permeability convenient parameter characterises flow, correlating structure openness (interconnectivity window size), tortuosity hence shear rates. Using experimentally validated computational simulations, we demonstrate additive properties controlling surface roughness at microstructual level (microns), altering strut ordering density mesoscopic (millimetre).