作者: Mustafa Malik Ghulam , Sumaira Kousar , Harsh Vardhan
DOI: 10.1007/978-81-322-2172-2_20
关键词: Computational biology 、 Genome 、 RNA editing 、 Gene 、 RNA splicing 、 Genome size 、 Biogenesis 、 Bioinformatics 、 Mitochondrion 、 Biology 、 Nuclear DNA
摘要: The semi-autonomous nature of mitochondria provides avenues to understand the evolution cellular functions, genome and regulatory circuit connecting gene expression functions. compromised its size for functional compatibility cell, this transition has been started approximately three billion years ago, when bacteria with unique energy-producing capabilities took residence in a proto-eukaryotic cell. In course symbiotic relationship, bacterium transferred many genes host nucleus, creating modern nuclear DNA (nDNA) genome. Since their discovery 1840 (called bioblast), great progress made understanding central role regulation energy metabolism nonetheless as key determinant fate. mitochondrial genomic sequence database is available majority species used scientific model address current questions. Herein omics give an edge at transcriptional, post-transcriptional (splicing RNA editing), translational post-translational level, complex composition, biogenesis cell death. Where necessary, readers are referred related detailed studies.