The histopathology of Langerhans cell histiocytosis.

作者: B E Favara , R Jaffe

DOI:

关键词: HistiocyteHistiocytosisCD1Dermatopathic lymphadenopathyLangerhans cell histiocytosisPathologyBiologyHistopathologyDifferential diagnosisJuvenile xanthogranuloma

摘要: Selected aspects of the histopathology Langerhans cell histiocytosis representing diagnostic difficulty and/or controversy are presented with emphasis on composition pathological lesions. Lesional phenotypes and factors influencing variations noted. Features several skin-based histiocytic disorders, dermatopathic lymphadenopathy Rosai-Dorfman disease compared. Associations between juvenile xanthogranuloma malignant disorders considered. Observations potential significance in eventual elucidation pathogenesis these enigmatic diseases presented.

参考文章(34)
W Kasinrerk, T Baumruker, O Majdic, W Knapp, H Stockinger, CD1 molecule expression on human monocytes induced by granulocyte-macrophage colony-stimulating factor. Journal of Immunology. ,vol. 150, pp. 579- 584 ,(1993)
Ken Hashimoto, Electron Microscopic Study of Reticulohistiocytoma Archives of Dermatology. ,vol. 107, pp. 263- 270 ,(1973) , 10.1001/ARCHDERM.1973.01620170071020
Peter Petzelbauer, Dagmar Födinger, Klemens Rappersberger, Beatrix Volc-Platzer, Klaus Wolff, CD68 positive epidermal dendritic cells Journal of Investigative Dermatology. ,vol. 101, pp. 256- 261 ,(1993) , 10.1111/1523-1747.EP12365183
Euan M. McMillan, G.Bennett Humphrey, Lloyd Stoneking, Lewis C. Strauss, Curt I. Civin, Toru Abo, Charles Balch, Analysis of histiocytosis X infiltrates with monoclonal antibodies directed against cells of histiocytic, lymphoid, and myeloid lineage Clinical Immunology and Immunopathology. ,vol. 38, pp. 295- 301 ,(1986) , 10.1016/0090-1229(86)90239-4
M B M Teunissen, J. Wormmeester, S R Krieg, P J Peters, I M C Vogels, M L Kapsenberg, J D Bos, Human Epidermal Langerhans Cells Undergo Profound Morphologic and Phenotypical Changes During In Vitro Culture Journal of Investigative Dermatology. ,vol. 94, pp. 166- 173 ,(1990) , 10.1111/1523-1747.EP12874439
Michaël G.H. Betjes, Mariëlle C. Haks, Cees W. Tuk, Robert H.J. Beelen, Monoclonal antibody EBM11 (anti-CD68) discriminates between dendritic cells and macrophages after short-term culture. Immunobiology. ,vol. 183, pp. 79- 87 ,(1991) , 10.1016/S0171-2985(11)80187-7
William D. Travis, Zea Borok, James H. Roum, Jun Zhang, Irwin Feuerstein, Victor J. Ferrans, Ronald G. Crystal, Pulmonary Langerhans cell granulomatosis (histiocytosis X). A clinicopathologic study of 48 cases. The American Journal of Surgical Pathology. ,vol. 17, pp. 971- 986 ,(1993) , 10.1097/00000478-199310000-00002
Franco Bonetti, Daniel M. Knowles, Marco Chilosi, Roberto Pisa, Sergio Fiaccavento, Nicola Rizzuto, Giuseppe Zamboni, Fabio Menestrina, Luciano Fiore-Donati, A distinctive cutaneous malignant neoplasm expressing the Langerhans cell phenotype. Synchronous occurrence with B-chronic lymphocytic leukemia. Cancer. ,vol. 55, pp. 2417- 2425 ,(1985) , 10.1002/1097-0142(19850515)55:10<2417::AID-CNCR2820551020>3.0.CO;2-9
Neil S Goldberg, Kenneth Bauer, Steven T Rosen, William A Caro, Robert J Marder, Charles Zugerman, Sambasiva Rao, Daina Variakojis, Histiocytosis X. Flow cytometric DNA-content and immunohistochemical and ultrastructural analysis Archives of Dermatology. ,vol. 122, pp. 446- 450 ,(1986) , 10.1001/ARCHDERM.122.4.446