What is the Significance of the Circumferential Margin in Locally Advanced Rectal Cancer After Neoadjuvant Chemoradiotherapy?

作者: Atthaphorn Trakarnsanga , Mithat Gonen , Jinru Shia , Karyn A. Goodman , Garrett M. Nash

DOI: 10.1245/S10434-012-2722-7

关键词: Surgical oncologyMedicineRadiologyNeoadjuvant therapyOncologyColorectal cancerChemoradiotherapyTotal mesorectal excisionInternal medicineSurvival rateProspective cohort studyAdenocarcinoma

摘要: Background The circumferential resection margin (CRM) is highly prognostic for local recurrence in rectal cancer surgery without neoadjuvant treatment. However, its significance in the …

参考文章(15)
T. E. Bernstein, B. H. Endreseth, P. Romundstad, A. Wibe, , Circumferential resection margin as a prognostic factor in rectal cancer. British Journal of Surgery. ,vol. 96, pp. 1348- 1357 ,(2009) , 10.1002/BJS.6739
Iris D Nagtegaal, Corrie AM Marijnen, Elma Klein Kranenbarg, Cornelis JH van de Velde, J Han JM van Krieken, Pathology Review Committee the Cooperative Clinical Investigators, Circumferential margin involvement is still an important predictor of local recurrence in rectal carcinoma: not one millimeter but two millimeters is the limit. The American Journal of Surgical Pathology. ,vol. 26, pp. 350- 357 ,(2002) , 10.1097/00000478-200203000-00009
I.J Adam, I.G Martin, Pj Finan, D Johnston, M.O Mohamdee, N Scott, M.F Dixon, P Quirke, Role of circumferential margin involvement in the local recurrence of rectal cancer The Lancet. ,vol. 344, pp. 707- 711 ,(1994) , 10.1016/S0140-6736(94)92206-3
Martin R. Weiser, Hak-Mien Quah, Jinru Shia, José G. Guillem, Philip B. Paty, Larissa K. Temple, Karyn A. Goodman, Bruce D. Minsky, W Douglas Wong, Sphincter preservation in low rectal cancer is facilitated by preoperative chemoradiation and intersphincteric dissection. Annals of Surgery. ,vol. 249, pp. 236- 242 ,(2009) , 10.1097/SLA.0B013E318195E17C
D. F. M. de Haas-Kock, C. G. M. I. Baeten, J. J. Jager, J. A. Langendijk, L. J. Schouten, A. Volovics, J. W. Arends, Prognostic significance of radial margins of clearance in rectal cancer. British Journal of Surgery. ,vol. 83, pp. 781- 785 ,(2005) , 10.1002/BJS.1800830617
Iris D. Nagtegaal, Phil Quirke, What Is the Role for the Circumferential Margin in the Modern Treatment of Rectal Cancer Journal of Clinical Oncology. ,vol. 26, pp. 303- 312 ,(2008) , 10.1200/JCO.2007.12.7027
Hak‐Mien Quah, Joanne F. Chou, Mithat Gonen, Jinru Shia, Deborah Schrag, Leonard B. Saltz, Karyn A. Goodman, Bruce D. Minsky, W. Douglas Wong, Martin R. Weiser, Pathologic stage is most prognostic of disease‐free survival in locally advanced rectal cancer patients after preoperative chemoradiation Cancer. ,vol. 113, pp. 57- 64 ,(2008) , 10.1002/CNCR.23516
Ingrid S. Martijnse, Ralph L. Dudink, Nicholas P. West, Dareczka Wasowicz, Grard A. Nieuwenhuijzen, Ineke van Lijnschoten, Hendrik Martijn, Valery E. Lemmens, Cornelis J. van de Velde, Iris D. Nagtegaal, Phil Quirke, Harm J. Rutten, Focus on Extralevator Perineal Dissection in Supine Position for Low Rectal Cancer Has Led to Better Quality of Surgery and Oncologic Outcome Annals of Surgical Oncology. ,vol. 19, pp. 786- 793 ,(2012) , 10.1245/S10434-011-2004-9
N. R. Hall, P. J. Finan, T. Al-Jaberi, C. S. Tsang, S. R. Brown, M. F. Dixon, P. Quirke, Circumferential margin involvement after mesorectal excision of rectal cancer with curative intent. Predictor of survival but not local recurrence Diseases of The Colon & Rectum. ,vol. 41, pp. 979- 983 ,(1998) , 10.1007/BF02237384