AN ASSESSMENT OF URINARY AND PLASMA STEROID ESTIMATIONS FOR MONITORING TREATMENT OF ANOVULATION WITH GONADOTROPHINS

摘要: Summary Total urinary oestrogens (UE), plasma oestradiol-17β (PE2), progesterone and pregnanediol values were estimated during 28 cycles of treatment with human menopausal gonadotrophins (HMG) chorionic gonadotrophin (HCG) in seven patients primary or secondary amenorrhoea who complained infertility. Ovulation occurred 23 courses three became pregnant. PE2 estimations gave a more accurate day to assessment the response than UE values. Monitoring should reduce any tendency overstimulation HMG allow timing first HCG injection which is critical for successful ovulatory response. The dose an effective stimulus ovulation when administered on peak after peak. appeared be ineffective if given subsequent this time two days last stimulation.