Oxidative stress, cardiolipin and mitochondrial dysfunction in nonalcoholic fatty liver disease
DOI: 10.3748/WJG.V20.I39.14205
关键词: Pathology 、 Population 、 Internal medicine 、 Mitochondrial respiratory chain 、 Endocrinology 、 Nonalcoholic fatty liver disease 、 Steatohepatitis 、 Chronic liver disease 、 Cardiolipin 、 Oxidative stress 、 Inner mitochondrial membrane 、 Biology
摘要: Nonalcoholic fatty liver disease (NAFLD) is today considered the most common form of chronic liver disease, affecting a high proportion of the population worldwide. NAFLD encompasses a large spectrum of liver damage, ranging from simple steatosis to steatohepatitis, advanced fibrosis and cirrhosis. Obesity, hyperglycemia, type 2 diabetes and hypertriglyceridemia are the most important risk factors. The pathogenesis of NAFLD and its progression to fibrosis and chronic liver disease is still unknown. Accumulating evidence …
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