Production of isoprenoids
作者： Julie Maurina-Brunker , James R. Millis , Thomas W. McMullin
DOI:
关键词: Stereochemistry 、 Mevalonic acid 、 Mevalonate pathway 、 Nucleic acid 、 Isopentenyl pyrophosphate 、 Terpenoid 、 Phosphomevalonic acid 、 Enzyme 、 Biology 、 Biochemistry 、 Yeast
摘要: A recombinant yeast that makes an isoprenoid compound is provided. The comprises endogenous mevalonate pathway comprising (i) enzyme converts acetyl-CoA to acetoacetyl-CoA, (ii) acetoacetyl-CoA hydroxymethylglutaryl-CoA, (iii) hydroxymethylglutaryl-CoA mevalonic acid, (iv) acid phosphomevalonic (v) phosphomevalonate, and (vi) phosphomevalonate isopentenyl pyrophosphate. further heterologous nucleic sequences encoding Carbon flow through the increased in compared a does not comprise molecule acid.
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