Probe set for analyzing a DNA sample and method for using the same

摘要: This disclosure provides, inter alia, a probe system for analyzing nucleic acid sample. In some embodiments, the may comprise: set of identifier oligonucleotides sequence B, splint formula X'-A'-B'-Z', wherein A' is complementary to genomic fragment and B' at least one member oligonucleotides, or more sequences comprising X Z. Each oligonucleotide capable hybridizing sequences, fragment, thereby producing ligatable complex X-A-B-Z. The can be used identify chromosome aneuploidy in cell free DNA, example.