Efficacy of a behavior change program on cardiovascular parameters in patients with hypertension: a randomized controlled trial.
作者： Aline Mendes Gerage , Tânia Rosane Bertoldo Benedetti , Bruno Remígio Cavalcante , Breno Quintella Farah , Raphael Mendes Ritti-Dias
DOI: 10.31744/EINSTEIN_JOURNAL/2020AO5227
关键词: In patient 、 Exercise physiology 、 Randomized controlled trial 、 Physical therapy 、 Behavior change 、 Program evaluation 、 Blood pressure 、 Arterial stiffness 、 Trial registration 、 Medicine
摘要: Objective To investigate the efficacy of a behavior change program named Vida Ativa Melhorando Saude on cardiovascular parameters in hypertensive patients. Methods Ninety patients aged over 40 years were randomly allocated to one two groups: or Control (n=45 respectively). Patients group took part aimed encourage changes physical activity levels and eating habits, according Social Cognitive Theory. The consisted 90-minute weekly meetings conducted by therapist dietitian. One chapter educational material (workbook) provided was discussed per meeting. Participants Group attended single educative lecture lifestyle changes. Brachial central blood pressure, arterial stiffness endothelial function measured pre- post-intervention. Results led reduction brachial (131.3±15.8mmHg 125.1±17.3mmHg; p 0.05). Conclusion improved pressure microvascular reactivity Trial registration: ClinicalTrials.gov: NCT02257268.
einstein.br参考文章(32)
Luc F. Van Gaal, Ilse L. Mertens, Christophe E. De Block, Mechanisms linking obesity with cardiovascular disease Nature. ,vol. 444, pp. 875- 880 ,(2006) , 10.1038/NATURE05487
Robert H. Eckel, John M. Jakicic, Jamy D. Ard, Janet M. de Jesus, Nancy Houston Miller, Van S. Hubbard, I-Min Lee, Alice H. Lichtenstein, Catherine M. Loria, Barbara E. Millen, Cathy A. Nonas, Frank M. Sacks, Sidney C. Smith, Laura P. Svetkey, Thomas A. Wadden, Susan Z. Yanovski, 2013 AHA/ACC Guideline on Lifestyle Management to Reduce Cardiovascular Risk Circulation. ,vol. 129, pp. 2960- 2984 ,(2014) , 10.1161/01.CIR.0000437740.48606.D1
T Tagawa, T Imaizumi, T Endo, M Shiramoto, Y Harasawa, A Takeshita, Role of nitric oxide in reactive hyperemia in human forearm vessels. Circulation. ,vol. 90, pp. 2285- 2290 ,(1994) , 10.1161/01.CIR.90.5.2285
S. Hollis, F. Campbell, What is meant by intention to treat analysis? Survey of published randomised controlled trials BMJ. ,vol. 319, pp. 670- 674 ,(1999) , 10.1136/BMJ.319.7211.670
Thomas Lauer, Christian Heiss, Michael Preik, Jan Balzer, Dieter Hafner, Bodo E Strauer, Malte Kelm, Reduction of peripheral flow reserve impairs endothelial function in conduit arteries of patients with essential hypertension. Journal of Hypertension. ,vol. 23, pp. 563- 569 ,(2005) , 10.1097/01.HJH.0000160213.40855.B7
Seiji Maeda, Asako Miyaki, Hiroshi Kumagai, Miki Eto, Rina So, Kiyoji Tanaka, Ryuichi Ajisaka, Lifestyle modification decreases arterial stiffness and plasma asymmetric dimethylarginine level in overweight and obese men Coronary Artery Disease. ,vol. 24, pp. 583- 588 ,(2013) , 10.1097/MCA.0B013E3283647A99
Thor Tejada, Alessia Fornoni, Oliver Lenz, Barry J. Materson, Nonpharmacologic therapy for hypertension: does it really work? Current Cardiology Reports. ,vol. 8, pp. 418- 424 ,(2006) , 10.1007/S11886-006-0099-6
Hiroshi Kumagai, Asako Zempo-Miyaki, Toru Yoshikawa, Takehiko Tsujimoto, Kiyoji Tanaka, Seiji Maeda, Lifestyle modification increases serum testosterone level and decrease central blood pressure in overweight and obese men Endocrine Journal. ,vol. 62, pp. 423- 430 ,(2015) , 10.1507/ENDOCRJ.EJ14-0555
D T Beck, J S Martin, D P Casey, R W Braith, Exercise training improves endothelial function in resistance arteries of young prehypertensives Journal of Human Hypertension. ,vol. 28, pp. 303- 309 ,(2014) , 10.1038/JHH.2013.109
Todd J. Anderson, Francois Charbonneau, Lawrence M. Title, Jean Buithieu, M. Sarah Rose, Heather Conradson, Kathy Hildebrand, Marinda Fung, Subodh Verma, Eva M. Lonn, Microvascular Function Predicts Cardiovascular Events in Primary Prevention Long-Term Results From the Firefighters and Their Endothelium (FATE) Study Circulation. ,vol. 123, pp. 163- 169 ,(2011) , 10.1161/CIRCULATIONAHA.110.953653