Autoradiographic localization of beta-adrenergic receptors in rabbit eye.
作者： P Lapalus , G Moulin , M Kosina-Boix , P P Elena
DOI:
关键词: Chemistry 、 Retina 、 Pathology 、 Receptor 、 Ciliary processes 、 Extraocular muscles 、 Corneal endothelium 、 Choroid 、 Epithelium 、 Iodocyanopindolol
摘要: Using an in vitro autoradiography, beta-adrenergic receptors were localized the rabbit eye. Autoradiograms generated by apposition of isotope-sensitive film to slide-mounted eye sections, labelled with [125I](-)Iodocyanopindolol. A high density silver grains was obtained conjunctival, corneal and ciliary process epithelium. Binding sites also present endothelium, iris epithelium, lens choroid extraocular muscles. In some areas, retina labelled. Studies compounds showed that majority receptors, detectable beta2 type
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