The Quantitative Assessment of Gd-DTPA in Contrast Enhanced Magnetic Resonance Angiography

作者: C.-C. Hsiao , J.-C. Jao , Y.-N. Ting , H.-B. Pan , S.-T. Lai

DOI: 10.1109/IEMBS.2005.1616687

关键词: SalineContrast (vision)Quantitative assessmentNuclear medicinePotential toxicityImaging phantomLesion detectionMagnetic resonance angiographyMedicineRadiologyPulse (signal processing)

摘要: Recently, the use of MRI contrast agents has been proven to be substantially improved sensitivity and specificity in many clinical applications. CE-MRA higher blood signal based on T1 T2-shortening property agents, so that even small vessels can visualized. The improve lesion detection characterization. routinely used dose routine examinations only relies weight subject. purpose this study is obtain clinically optimal for 3D-TOF (time-of-flight) pulse sequences examinations. In phantom study, ten test tubes were filled with saline mixed different Gd-DTPA. It found Gd-DTPA by using 20 mM. Also, there no differences doses between Omniscan Magnivist results show consistent high quality images might obtained 0.25M (half dose) 3~4 cc/sec injection rate all cases. benefits minimize potential toxicity. Additionally, decrease cost achieved. expected provide recommended enhanced MRA diagnosis

参考文章(22)
Douglas R De Corato, Glenn A Krinsky, Neil M Rofsky, James P Earls, Jonathan Lebowitz, Jeffery C Weinreb, Contrast-enhanced hepatic mri: Comparison of half-dose and standard-dose gadolinium dtpa administration in lesion characterization with T1-weighted gradient echo sequences Clinical Imaging. ,vol. 23, pp. 302- 310 ,(1999) , 10.1016/S0899-7071(99)00150-3
Richard E. A. Walker, Stephen J. Eustace, Whole-body magnetic resonance imaging: techniques, clinical indications, and future applications Seminars in Musculoskeletal Radiology. ,vol. 5, pp. 5- 20 ,(2001) , 10.1055/S-2001-12923
C-C HSIAO, J-C JAO, Y-N TING, H-B PAN, P-C CHEN, OPTIMAL DOSE OF MR CONTRAST AGENT IN T1-WEIGHTED MRI Biomedical Engineering: Applications, Basis and Communications. ,vol. 16, pp. 331- 336 ,(2004) , 10.4015/S1016237204000451
Mark S. Cohen, Real-Time Functional Magnetic Resonance Imaging Methods. ,vol. 25, pp. 201- 220 ,(2001) , 10.1006/METH.2001.1235
Fred. J. Taussig, Irradiation in Cancer of the Cervix Radiology. ,vol. 5, pp. 5- 8 ,(1925) , 10.1148/5.1.5
Michael V. Knopp, Frederik L. Giesel, Hani Marcos, Hendrik von Tengg-Kobligk, Peter Choyke, Dynamic contrast-enhanced magnetic resonance imaging in oncology. Topics in Magnetic Resonance Imaging. ,vol. 12, pp. 301- 308 ,(2001) , 10.1097/00002142-200108000-00006
Giovanni Morana, Luigi Grazioli, Marco Testoni, Paolo Caccia, Carlo Procacci, Contrast agents for hepatic magnetic resonance imaging. Topics in Magnetic Resonance Imaging. ,vol. 13, pp. 117- 150 ,(2002) , 10.1097/00002142-200206000-00002
Thomas H Helbich, Contrast-enhanced magnetic resonance imaging of the breast. European Journal of Radiology. ,vol. 34, pp. 208- 219 ,(2000) , 10.1016/S0720-048X(00)00200-X
Satoru Takahashi, Takamichi Murakami, Manabu Takamura, Tonsok Kim, Masatoshi Hori, Yoshifumi Narumi, Hironobu Nakamura, Is half-dose contrast-enhanced three-dimensional MR angiography sufficient for the abdominal aorta and pelvis? Journal of Magnetic Resonance Imaging. ,vol. 19, pp. 194- 201 ,(2004) , 10.1002/JMRI.10443
W. Gregory Hundley, Craig A. Hamilton, Pairoj Rerkpattanapipat, Magnetic resonance imaging assessment of cardiac function. Current Cardiology Reports. ,vol. 5, pp. 69- 74 ,(2003) , 10.1007/S11886-003-0040-1