Behavioral Genetics: Affective Disorders and Schizophrenia

摘要: Genetic Investigations in Affective Disorders and Schizophrenia. studies on these conditions have a long history. After many case reports the pre-Mendelian area, classic work by Rudin appeared 1916 [45]. This owed its statistical sophistication to collaboration with Weinberg, of “Hardy-Weinberg” fame, became paradigmatic model for phenotypic-biometric approach such disorders. Following this paradigm, family twin were carried out. These clearly established that genetic variability plays major part causing affective diseases schizophrenia (Fig.16.1, 16.2). Moreover, contributed much increasing methodology establishing empirical risk figures needed counseling [28]. results, however, left an number research workers dissatisfied, there is list — mostly futile attempts move analysis level closer gene action discover biological bases