Development of Z-scores for fetal cardiac dimensions from echocardiography.

摘要: Objectives Z-scores for cardiac dimensions are well established in postnatal life, but have yet to be developed fetal dimensions. These would of real advantage the clinician accurately quantifying size and growth researcher by allowing mathematical comparison differing subgroups a disease. The purpose this observational study, conducted at tertiary medicine cardiology units, was produce formulae nomograms computation Z-scores from knowledge femur length (FL), biparietal diameter (BPD) or gestational age (GA) using echocardiography. Methods Seventeen were measured 130 pregnant women with singleton fetuses 15–39 weeks. Regression equations derived relating all FL, BPD GA. From calculations, then Z-score computation. Results The relationships between GA described following natural log transformation. analysis, FL (taken as an expression size) had highest correlation nomograms, specific structures could estimated echocardiographically measurements. Conclusions This study allowed life 17 Previous studies normal data qualitative assessment where abnormal lay regard range. allow quantitative analysis such lie relative mean. This permits exact hearts particularly congenitally is important analyzing planning treatment strategies. Copyright © 2005 ISUOG. Published John Wiley & Sons, Ltd.