On the nature of Castle's hemopoietic factor.
作者： SHEILA T. CALLENDER , L. G. LAJTHA
DOI: 10.1182/BLOOD.V6.12.1234.1234
关键词: Megaloblasts 、 Internal medicine 、 Cyanocobalamin 、 Chemistry 、 Endocrinology 、 Haematopoiesis 、 Ripening 、 Thermolabile 、 Intrinsic factor 、 Vitamin B12 、 Stomach
摘要: 1. Normal gastric juice (intrinsic factor) and vitamin B12 together form a thermolabile hemopoietic factor which ripens megaloblasts in vitro, both alone being inactive. 2. The normal serum vitro also appears to be thermolabile, heating 56 C. for 2 hours destroying some of its activity. 3. relationship these factors is discussed an extra-gastric as well source intrinsic postulated.
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