Serum calcitonin may falsely estimate tumor burden in chronic hypercalcemia: a case of prostatic and multiple bone metastases from medullary thyroid cancer.
作者： Hee Kyung Kim , Woo Kyun Bae , Yoo Duk Choi , Hyun Jeong Shim , Jee Hee Yoon
关键词: Pathology 、 Lymph node 、 Metastasis 、 Carcinoembryonic antigen 、 Medullary thyroid cancer 、 Thyroid 、 Medicine 、 Prostate biopsy 、 Calcitonin 、 Prostate
摘要: Background: Medullary thyroid cancer (MTC) is a calcitonin (Ct)-secreting tumor of the parafollicular or C cells gland. Higher serum Ct levels are associated with larger size, distant metastases, and prognosis. We report herein case prostate multiple bone metastases nonfamilial MTC mildly elevated levels. Patient Findings: A 73-year-old man who was found to have 2.5 cm in left lobe cervical lymph node presented confused mental status because severe hypercalcemia (albumin-modified calcium concentration 15.2 mg/dL) metastases. Prostate biopsy performed patient had frequent urination prostate-specific antigen (5.297 ng/mL). Histologically, diagnosed as metastasis, forming tissue architecture closely resembling previously MTC, were positive for Ct, carcinoembryonic antigen, transcription ...
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