First episode psychosis and comorbid ADHD, autism and intellectual disability
作者： Pontus Strålin , Jerker Hetta
DOI: 10.1016/J.EURPSY.2018.09.007
关键词: Cohort 、 Intellectual disability 、 Psychosis 、 Schizophrenia 、 Autism 、 Medicine 、 First episode psychosis 、 Comorbidity 、 Psychiatry 、 Antipsychotic
摘要: Abstract Background Comorbidity between neurodevelopmental disorders and psychotic is common, but little known about how influence the presentation outcome of first episode psychosis. Methods A nation-wide cohort (n = 2091) with a hospitalization for psychosis 2007–2011 at ages 16–25 at intake was identified from Swedish population registries. Comorbid diagnoses were ADHD also by dispensations psychostimulants before hospitalization. Data registers on hospitalizations antipsychotic psychostimulant medications during year 2 years after analysed. Self-harm substance use ICD10 codes hospitalizations. Results 2.5% diagnosis intellectual disability, 5.0% autism 8.1% ADHD. larger proportion cases Autism (OR = 1.8, p Conclusions Psychosis comorbid associated high risks self-harm, while disability longer treatment higher doses medication.
sci-hub.se 参考文章(33)
Katharine Chisholm, Ashleigh Lin, Ahmad Abu-Akel, Stephen J. Wood, The association between autism and schizophrenia spectrum disorders: A review of eight alternate models of co-occurrence Neuroscience & Biobehavioral Reviews. ,vol. 55, pp. 173- 183 ,(2015) , 10.1016/J.NEUBIOREV.2015.04.012
Srividya Iyer, Ashok Malla, Ridha Joober, Emmanuelle Levy, Alexandru Traicu, Psychotic disorders comorbid with attention-deficit hyperactivity disorder: an important knowledge gap. The Canadian Journal of Psychiatry. ,vol. 60, ,(2015)
Sally-Ann Cooper, Elita Smiley, Jillian Morrison, Linda Allan, Andrew Williamson, Janet Finlayson, Alison Jackson, Dipali Mantry, Psychosis and adults with intellectual disabilities Social Psychiatry and Psychiatric Epidemiology. ,vol. 42, pp. 530- 536 ,(2007) , 10.1007/S00127-007-0197-9
Michael F. Green, Cognitive impairment and functional outcome in schizophrenia and bipolar disorder. The Journal of Clinical Psychiatry. ,vol. 67, pp. 3- 8 ,(2006) , 10.4088/JCP.1006E12
ELYSA J. MARCO, LEIGHTON B.N. HINKLEY, SUSANNA S. HILL, SRIKANTAN S. NAGARAJAN, Sensory Processing in Autism: A Review of Neurophysiologic Findings Pediatric Research. ,vol. 69, pp. 48- 54 ,(2011) , 10.1203/PDR.0B013E3182130C54
James M Gold, Daniel R Weinberger, Cognitive deficits and the neurobiology of schizophrenia Current Opinion in Neurobiology. ,vol. 5, pp. 225- 230 ,(1995) , 10.1016/0959-4388(95)80030-1
Cecilie Frejstrup Maibing, Carsten Bøcker Pedersen, Michael Eriksen Benros, Preben Bo Mortensen, Søren Dalsgaard, Merete Nordentoft, Risk of Schizophrenia Increases After All Child and Adolescent Psychiatric Disorders: A Nationwide Study Schizophrenia Bulletin. ,vol. 41, pp. 963- 970 ,(2015) , 10.1093/SCHBUL/SBU119
Clare S Allely, The association of ADHD symptoms to self-harm behaviours: a systematic PRISMA review. BMC Psychiatry. ,vol. 14, pp. 133- 133 ,(2014) , 10.1186/1471-244X-14-133
Johanna C. Badcock, Milan Dragović, Flavie A.V. Waters, Assen Jablensky, Dimensions of intelligence in schizophrenia: evidence from patients with preserved, deteriorated and compromised intellect. Journal of Psychiatric Research. ,vol. 39, pp. 11- 19 ,(2005) , 10.1016/J.JPSYCHIRES.2004.05.002
Jess Hamlyn, Michael Duhig, John McGrath, James Scott, Modifiable risk factors for schizophrenia and autism--shared risk factors impacting on brain development. Neurobiology of Disease. ,vol. 53, pp. 3- 9 ,(2013) , 10.1016/J.NBD.2012.10.023