Larva lights: A decade of photoaffinity labeling with juvenile hormone analogues

作者: Glenn D. Prestwich , Kazushige Touhara , Lynn M. Riddiford , Bruce D. Hammock

DOI: 10.1016/0965-1748(94)90104-X

关键词: CockroachBiochemistrySex pheromoneInternal medicineJuvenile hormoneSphingidaeEndocrinologyPhotoaffinity labelingLepidoptera genitaliaManduca sextaBinding proteinBiology

摘要: The introduction of photoaffinity labeling into the mode action insect hormones and pheromones started 12 yr ago with juvenile hormone binding proteins (JHBPs) from cockroaches in laboratory late John K. Koeppe. Applying this technique to Manduca sexta led ultimately a three-laboratory collaborative project that has begun dissect molecular basis for JH transport, metabolism, nuclear gene activation Lepidoptera. This review provides (1) history first experiments; (2) an idea breadth arthropod classes Insecta, Crustacea, Arachnida; (3) evidence depth unearthing key details about three different types M. sexta.

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