Zoonotic potential of Newcastle disease virus: Old and novel perspectives related to public health

摘要: Newcastle disease virus (NDV) has a worldwide distribution, causing lethal infection in wide range of avian species. Affected birds develop respiratory, digestive and neurologic symptoms with profound immunosuppression. Mild systemic (ND) restricted to the respiratory neurological systems can be observed humans other non-avian hosts. Evidence ND its genome-based detection have been reported Bovidae (cattle sheep), Mustelidae (mink), Cercetidae (hamster), Muridae (mice), Leporidae (rabbit), Camelidae (camel), Suidae (pig), Cercophithecidae (monkeys) Hominidae (humans). Owing frequent outbreaks poultry workers, individuals engaged veterinary field, including production or evisceration vaccine units constantly at much higher risk than general population. A form described immunocompromised species mink, pig cattle demonstrating capability NDV cross barriers. Therefore, contact infectious material and/or affected pose zoonosis raise public health concerns. The broad expanding host maintenance within hampers control, particularly disease-endemic settings.