Chlamydia trachomatis and cancer

作者: J. Paavonen

DOI: 10.1136/STI.77.3.154

关键词: Tubal factor infertilityRisk factorChlamydia trachomatisImmunologyCervical cancerCancerHPV infectionChlamydiaPelvic inflammatory diseaseMedicine

摘要: Genital Chlamydia trachomatis infections have been recognised as a major public health problem. The World Health Organization (WHO) estimates that 50 million cases of C infection occur each year worldwide.1 is the cause mucopurulent cervicitis, pelvic inflammatory disease, tubal factor infertility, and ectopic pregnancy.2–5 Thus, healthcare costs due to complications caused by are enormous. Cervical cancer most common in women worldwide. Epidemiological studies shown early sexual activity risk for cervical cancer.6 High human papillomavirus (HPV) types found practically all carcinomas.7 evidence linking oncogenic HPV aetiology carcinoma beyond doubt. DNA based longitudinal confirmed seroepidemiological findings past predisposes development carcinoma.8, 9 Since also marker activity, an association between has suggested. Previous case-control cytological or serological role neoplasia.10–12 Recent associated with carcinoma.13, 14 This remains after adjustment smoking serum antibodies …

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