Dysfunctional Pro-Ceramide, ER Stress, and Insulin/IGF Signaling Networks with Progression of Alzheimer's Disease
作者： Suzanne M. de la Monte , Edward Re , Lisa Longato , Ming Tong
关键词: Neurodegeneration 、 Insulin 、 Endocrinology 、 Ceramide 、 Insulin resistance 、 Endoplasmic reticulum 、 Signal transduction 、 Downregulation and upregulation 、 Unfolded protein response 、 Internal medicine 、 Biology
摘要: … In Alzheimer’s disease (AD), brain insulin and insulin-like growth factor (IGF) resistance and … These findings support our hypothesis that in AD, a triangulated mal-signaling network …
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