作者: Susan Elisabeth Hinckfuss , Louise Brearley Messer
DOI: 10.1111/J.1600-9657.2008.00736.X
关键词: Medical prescription 、 Dentition 、 Cochrane Library 、 MEDLINE 、 Guideline 、 Tooth Avulsion 、 Evidence-based dentistry 、 Meta-analysis 、 Dentistry 、 Medicine
摘要: – Background: Current clinical guidelines recommend prescribing systemic antibiotic therapy (SAT) for patients having an avulsed permanent tooth replanted. The principles of evidence-based dentistry can be used to assess whether this is the best approach based on currently-available evidence. objective study was use answer PICO question: (P) a replanted tooth, (I) SAT, (C) compared with not (O) associated increased likelihood successful periodontal healing after replantation? Materials and methods: A literature search performed across four internet databases (Ovid Medline, Cochrane Library, PubMed, ISI Web Science), relevant citations (n = 35 702). Limiting those in English removing duplicates produced set titles (n = 14 742) that were sieved according principles. Relevant selected abstract assessment (n = 782), identifying papers examination (n = 74). Inclusion criteria applied three (326 total teeth) met final meta-analysis. Results: Meta-analyses found no statistically significant difference between or antibiotics acceptable without progressive root resorption (common odds ratio = 0.90, SE = 0.29, 95% confidence intervals = 0.51–1.58). Conclusion: evidence association SAT outcome inconclusive. This investigation as defined indicates there inconclusive from studies human teeth either contradict support guideline. Pending future research contrary, dentists are recommended follow current when replanting teeth.