Automated Segmentation of Foveal Avascular Zone in Fundus Fluorescein Angiography
作者： Yalin Zheng , Jagdeep Singh Gandhi , Alexandros N. Stangos , Claudio Campa , Deborah M. Broadbent
DOI: 10.1167/IOVS.09-4935
关键词: Reproducibility 、 Automated segmentation 、 Segmentation 、 Foveal avascular zone 、 Artificial intelligence 、 Computer vision 、 Fluorescein angiography 、 Fundus fluorescein angiography 、 Linear correlation 、 Foveal 、 Medicine
摘要: PURPOSE. To describe and evaluate the performance of a computerized automated segmentation technique for use in quantification foveal avascular zone (FAZ). METHODS. A FAZ using images from fundus fluorescein angiography (FFA) was applied to 26 transit-phase obtained patients with various grades diabetic retinopathy. The area containing first extracted original image smoothed by Gaussian kernel ( 1.5). An initializing contour manually placed inside iteratively moved program toward boundary. Five tests different curves were run on each assess reproducibility. accuracy also validated comparing results boundaries delineated medical retina specialists. Interobserver then evaluated delineations two experts. RESULTS. One-way analysis variance indicated that disparities between not statistically significant, signifying excellent reproducibility computer program. There significant linear correlation automation manual CONCLUSIONS. This can produce highly reproducible are comparable those made clinical It has potential assist detection management ischemia be integrated into grading systems. (Invest Ophthalmol Vis Sci. 2010;51:3653‐3659) DOI:10.1167/iovs.09-4935
arvojournals.org
sci-hub.se 参考文章(28)
Oliver Arend, Alon Harris, Andreas Remky, Reinhard Stüber, David Evans, Contrast sensitivity loss is coupled with capillary dropout in patients with diabetes. Investigative Ophthalmology & Visual Science. ,vol. 38, pp. 1819- 1824 ,(1997)
Lucia Ballerini, Genetic Snakes for Medical Images Segmentation Lecture Notes in Computer Science. pp. 59- 73 ,(1999) , 10.1007/10704703_5
Nikos Paragios, Stanley Osher, "Geometric Level Set Methods in Imaging, Vision, and Graphics" ,(2011)
A. M. MANSOUR, ANDREW SCHACHAT, GARY BODIFORD, ROBERT HAYMOND, Foveal avascular zone in diabetes mellitus. Retina-the Journal of Retinal and Vitreous Diseases. ,vol. 13, pp. 125- 128 ,(1993) , 10.1097/00006982-199313020-00006
J Conrath, R Giorgi, B Ridings, D Raccah, Metabolic factors and the foveal avascular zone of the retina in diabetes mellitus Diabetes & Metabolism. ,vol. 31, pp. 465- 470 ,(2005) , 10.1016/S1262-3636(07)70217-3
Marcus A Sleightholm, John Arnold, Eva M Kohner, None, Diabetic retinopathy: I. The measurement of intercapillary area in normal retinal angiograms Journal of Diabetic Complications. ,vol. 2, pp. 113- 116 ,(1988) , 10.1016/S0891-6632(88)80019-9
G. H. Bresnick, R. Condit, S. Syrjala, M. Palta, A. Groo, K. Korth, Abnormalities of the Foveal Avascular Zone in Diabetic Retinopathy Archives of Ophthalmology. ,vol. 102, pp. 1286- 1293 ,(1984) , 10.1001/ARCHOPHT.1984.01040031036019
Oliver Arend, Sebastian Wolf, Andreas Remky, William Eric Sponsel, Alon Harris, Bernd Bertram, Martin Reim, Perifoveal microcirculation with non-insulin-dependent diabetes mellitus Graefes Archive for Clinical and Experimental Ophthalmology. ,vol. 232, pp. 225- 231 ,(1994) , 10.1007/BF00184010
R. T. Smith, C. M. Lee, H. C. Charles, M. Farber, J. G. Cunha-Vaz, Quantification of diabetic macular edema. Archives of Ophthalmology. ,vol. 105, pp. 218- 222 ,(1987) , 10.1001/ARCHOPHT.1987.01060020072032
O Arend, A Remky, A Harris, B Bertram, M Reim, S Wolf, Macular microcirculation in cystoid maculopathy of diabetic patients. British Journal of Ophthalmology. ,vol. 79, pp. 628- 632 ,(1995) , 10.1136/BJO.79.7.628