9.8 G Protein Coupled Receptors
作者： D. Provasi , M. Filizola
DOI: 10.1016/B978-0-12-374920-8.00911-5
关键词: SUPERFAMILY 、 Small particles 、 Receptor 、 Computational biology 、 Biology 、 G protein-coupled receptor 、 Homology modeling 、 Membrane protein 、 Cell biology 、 Molecular model
摘要: The G protein-coupled receptor (GPCR) superfamily consists of numerous closely related membrane proteins that respond to a variety stimuli ranging from small particles large molecules. consequent initiation several different biological processes makes these receptors the most targeted group for development therapeutic drugs. Advances in structural, biochemical, and biophysical analyses GPCRs offer unique opportunity improve dynamic molecular models receptors. This chapter highlights results application computational approaches toward better understanding mechanisms underlying their diverse functions.
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