Infectious Disease risks associated with exposure to stressful environments

作者: Richard T. Meehan , Morey Smith , Clarence Sams

DOI: 10.4271/932140

关键词: Biologic responseIntensive care medicineRadiation exposureInfectious disease (medical specialty)SpaceflightInfectious illnessCrewMedicineToxicologyStressorSleep deprivation

摘要: Multiple environmental factors asociated with space flight can increase the risk of infectious illness among crewmembers thereby adversely affecting crew health and mission success. Host defences be impaired by multiple physiological psychological stressors including: sleep deprivation, disrupted circadian rhythms, separation from family, perceived danger, radiation exposure, possibly also direct indirect effects microgravity. Relevant human immunological data isolated or stressful environments including spaceflight will reviewed. Long-duration missions should include reliable hardware which supports sophisticated immunodiagnostic capabilities. Future advances in immunology molecular biology continue to provide therapeutic agents biologic response modifiers effectively selectively restore immune function has been depressed exposure stressors.

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