Autism and tuberous sclerosis.

作者: Max Wiznitzer

DOI: 10.1177/08830738040190090701

关键词: AutismCognitive impairmentComorbidityPopulationPsychiatryMedicinePediatricsAutism spectrum disorderBrain developmentBrain functionTuberous sclerosis

摘要: The co-occurrence of autism spectrum disorder and tuberous sclerosis complex has been recognized for decades. prevalence in the population is 1 to 4%, whereas features are present 25 50% individuals with complex. underlying reason this association might be a nonspecific disruption brain function owing complex, including tuber location, seizures their effect on development, cognitive impairment, disturbance development regions associated disorder, or, less likely, linkage between TSC gene an susceptibility gene. Awareness relationship important during evaluation either disorder. Better delineation its causative factors needed possible interventions. (J Child...

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