Is laparoscopy an advantage in the diagnosis of cirrhosis in chronic hepatitis C virus infection
作者： Perdita Wietzke-Braun
关键词: Hepacivirus 、 Alpha interferon 、 Hepatitis C 、 Liver biopsy 、 Cirrhosis 、 Internal medicine 、 Biopsy 、 Laparoscopy 、 Medicine 、 Retrospective cohort study 、 Gastroenterology 、 General Medicine
摘要: AIM: To evaluate the potential of laparoscopy in diagnosis cirrhosis and outcome interferon treatment HCV-infected patients. METHODS: In this retrospective study, diagnostic with laparoscopic liver biopsy was performed 72 consecutive patients chronic HCV infection. The presence or absence analyzed macroscopically by microscopically specimens. Clinical laboratory data interferon-alfa were compared between cirrhotic noncirrhotic RESULTS: Laparoscopically, seen 29.2 % (21/72) non-cirrhosis 70.8 (51/72) Cirrhotic significantly older a significant longer duration infection than Laboratory parameters (AST, y-GT, y-globulin fraction) measured higher as well lower (prothrombin index, platelet count) non-cirrhotic Histologically, confirmed 11.1 (8/72) non 88.9 (64/72). Patients (n=21) showed histologically 38.1 (8/21) noncirrhosis 61.9 (13/21). contrast, (n=51) all cases (51/51). Thirty-nine treated interferon-alfa, resulting 35.9 (14/39) sustained response 64.1 (25/39) response. Non-responders more responders. there no histological differences non-responders
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