Increased thermal stability of proteins in the presence of sugars and polyols
作者： Joan F. Back , David Oakenfull , Malcolm B. Smith
DOI: 10.1021/BI00590A025
关键词: Sugar 、 Polyol 、 Denaturation (biochemistry) 、 Hydrophobic effect 、 Sorbitol 、 Glycerol 、 Chemical engineering 、 Chemistry 、 Aqueous solution 、 Conalbumin
摘要: … protein amino groups resulted in an exothermic heat change … governed by the exposure of amino groups on denaturation) and … This was prevented by the lack at higher temperatures of …
acs.org
sci-hub.se 参考文章(27)
C.H. Giles, R.B. McKay, Studies in hydrogen bond formation. XI. Reactions between a variety of carbohydrates and proteins in aqueous solutions. Journal of Biological Chemistry. ,vol. 237, pp. 3388- 3392 ,(1962) , 10.1016/S0021-9258(19)70827-8
Charles D. Ball, Chester R. Hardt, Willard J. Duddles, THE INFLUENCE OF SUGARS ON THE FORMATION OF SULFHYDRYL GROUPS IN HEAT DENATURATION AND HEAT COAGULATION OF EGG ALBUMIN Journal of Biological Chemistry. ,vol. 151, pp. 163- 169 ,(1943) , 10.1016/S0021-9258(18)72124-8
JW Donovan, RA Beardslee, Heat stabilization produced by protein-protein association. A differential scanning calorimetric study of the heat denaturation of the trypsin-soybean trypsin inhibitor and trypsin-ovomucoid complexes. Journal of Biological Chemistry. ,vol. 250, pp. 1966- 1971 ,(1975) , 10.1016/S0021-9258(19)41670-0
J W Donovan, K D Ross, Iron binding to conalbumin. Calorimetric evidence for two distinct species with one bound iron atom. Journal of Biological Chemistry. ,vol. 250, pp. 6026- 6031 ,(1975) , 10.1016/S0021-9258(19)41153-8
Gordon Alderton, H.L. Fevold, DIRECT CRYSTALLIZATION OF LYSOZYME FROM EGG WHITE AND SOME CRYSTALLINE SALTS OF LYSOZYME Journal of Biological Chemistry. ,vol. 164, pp. 1- 5 ,(1946) , 10.1016/S0021-9258(18)43040-2
John E. Garrod, Thelma M. Herrington, Apparent molar volumes and temperatures of maximum density of dilute aqueous sucrose solutions The Journal of Physical Chemistry. ,vol. 74, pp. 363- 370 ,(1970) , 10.1021/J100697A023
D. G. Oakenfull, D. E. Fenwick, Effect of ethanol on hydrophobic interactions. Conductometric study of ion-pair formation by double-long-chain electrolytes The Journal of Physical Chemistry. ,vol. 78, pp. 1759- 1763 ,(1974) , 10.1021/J100610A018
E. W. Anacker, Richard D. Geer, Edwin H. Eylar, Dependence of micelle aggregation number on polar head structure. I. Light scattering by aqueous solutions of decylammonium salts and related surfactants The Journal of Physical Chemistry. ,vol. 75, pp. 369- 374 ,(1971) , 10.1021/J100673A013
P.L. Privalov, Thermal investigations of biopolymer solutions and scanning microcalorimetry FEBS Letters. ,vol. 40, pp. S133- S139 ,(1974) , 10.1016/0014-5793(74)80697-6
T. S. Lakshmi, P. K. Nandi, Effects of sugar solutions on the activity coefficients of aromatic amino acids and their N-acetyl ethyl esters The Journal of Physical Chemistry. ,vol. 80, pp. 249- 252 ,(1976) , 10.1021/J100544A008