作者: N. Ravinet , N. Bareille , A. Lehebel , A. Ponnau , C. Chartier
DOI: 10.1016/J.VETPAR.2013.12.031
关键词: Anthelmintic 、 Bulk tank 、 Herd 、 Grazing 、 Fenbendazole 、 Animal science 、 After treatment 、 Biology 、 Veterinary medicine 、 Milk production 、 Ice calving
摘要: Abstract To investigate future tools for targeted selective treatment against gastrointestinal nematodes (GIN) in adult dairy cows, we evaluated herd and individual cow factors associated with the post-treatment milk production (MP) response over time. A field trial involving 20 pasturing herds Western France was conducted autumn 2010 2011. In each herd, lactating cows were randomly allocated to a group (fenbendazole) (623 cows), or control (631 cows). Daily MP recorded from 2 weeks before until 10 14 after treatment. Individual serum anti- Ostertagia antibody levels (expressed as ODR), pepsinogen levels, faecal egg count (FEC), bulk tank ODR measured at time of Moreover, information regarding heifers’ grazing history collected assess Time Effective Contact (TEC, expressed months) GIN infective larvae first calving. TEC expected reflect development immunity GIN, TEC = 8 months cautious threshold which resistance re-infection be established. averaged by week analyzed using linear mixed models three nested random effects (cow within year). The overall effect significant but slight (maximum = +0.85 kg/d on 6 treatment), evolution treated cows’ differed significantly according several factors. At level, low-TEC responded better than high-TEC (≥8 herds; percentage positive FEC >22.6% (median value) those where it lower. primiparous days (DIM) 100, higher ODR, respectively. These results highlight variability response, suggesting that whole anthelmintic are not always appropriate, propose promising key criteria cows. Particularly, is an original criterion lends support simultaneous on-farm qualitative analysis management